Memphis, TN – October 8, 2025 –MEMPHIS, Tenn.— OrthoSouth is proud to announce that fellowship-trained spine surgeon Dr. John J. Eager has successfully completed the Mid-South’s first spinal fusion using Carlsmed’s aprevo® Personalized Spine Implant — an AI-informed, 3D-printed device built to each patient’s exact anatomy. The landmark procedure took place at Saint Francis Hospital – Memphis on August 28, 2025.

The aprevo® platform integrates advanced imaging, AI-driven 3D surgical planning, and precision titanium additive manufacturing to produce custom implants that restore targeted spinal alignment, optimize fit, and reduce mechanical complications compared to traditional “off-the-shelf” devices.

Proven Clinical Impact
Data from over 500 patients across multiple centers shows aprevo® delivers:

• Targeted Alignment: 82% of personalized implants achieved alignment within 5° of surgical goals.
• Enhanced Graft Contact: 94% average implant-to-endplate contact at one year.
• Subsidence Mitigation: 96% of personalized implants with zero subsidence at one year.
• Lower Revision Rates: <2% rate of revision for mechanical complications in adult spinal deformity cases.

“Completing the first aprevo® case in our region was an exciting milestone,” says Dr. Eager. “By correcting spinal alignment preoperatively and delivering that plan with a patient-specific implant, we reduce the risk of malalignment and recurrent pain — and give patients the best possible chance at long-term relief.”

Personalized Process in Five Steps

1. CT Imaging to create a detailed 3D spine model.
2. AI-Based Surgical Planning for alignment restoration and optimal fit.
3. Surgeon Review & Approval of the personalized implant design.
4. 3D Printing in Titanium to exact specifications.
5. Hospital Delivery for use in the planned fusion procedure.